Testosterone Cypionate Injection USP Uses, Side Effects, Interactions

Testosterone Cypionate Injection USP Uses, Side Effects, Interactions

This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. When filling your prescription, be sure to call ahead to make sure your pharmacy carries it. If you think you’ve used too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away. Testosterone cypionate is available as the brand-name drug Depo-Testosterone. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form androgens such as testosterone are produced by the the brand-name drug.

Testosterone is present in both males and females, but the levels are higher in males. In all people, it performs many important functions, influencing sexual development, libido, mood, and more. Testosterone cypionate is the most relatively affordable option.Injections are weekly or biweekly rather than daily. Some notice faster changes using injectable testosterone compared to other methods.This is suitable for those who have skin sensitivity to gels or patches. The lowest pharmacy price for 2, 1 mL 200 mg/mL vials of testosterone cypionate is $36, almost $90 cheaper than the highest pharmacy price. Unfortunately, hunting down the best price for prescription medications involves a lot of work. The novel route of buccal administration for TRT was initially approved by the USA FDA in 2003 (Striant®, Actient Pharmaceuticals LLC, Chesterbrook, PA, USA).

You can learn more about what to expect and see a diagram here. You might see a bruise or a little bit of bleeding if you hit a small blood vessel. If you notice a lot of swelling or pain or itching that lasts a while (into the next day) then contact your clinician. It is uncomfortable, but it should not be extremely painful. Over time, people have said they get more and more used to it.

Evaluate patients who report symptoms of pain, edema, warmth and erythema in the lower extremity for DVT and those who present with acute shortness of breath for PE. If a venous thromboembolic event is suspected, discontinue treatment with testosterone cypionate and initiate appropriate workup and management. Androgen therapy should be used cautiously in healthy males with delayed puberty. The effect on bone maturation should be monitored by assessing bone age of the wrist and hand every 6 months. In children, androgen treatment may accelerate bone maturation without producing compensatory gain in linear growth.

Various delivery methods are available, including injections, gels, patches, and pellets. The goal is to re-establish healthy testosterone levels and improve energy, mood, muscle mass, and sexual function (Basaria, 2010). A PK study evaluated serum levels of testosterone periodically for 14 days after administration of TC 200 mg IM in 11 hypogonadal men (42). The mean Cmax was supratherapeutic (1,112±297 ng/dL) and occurred between days four and five post-injection. After day 5, testosterone levels declined and by day 14 the mean Cavg approached 400 ng/dL.

During the therapy, people will usually visit their doctor every few months for monitoring. However, testosterone did have associations with weight gain. It is also unclear what effect testosterone may have on other aspects of menopause, and the right dosage is also a subject of research. To accelerate development, doctors may consider a short-term treatment with low dose testosterone, particularly if the child is experiencing distress or bullying. Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F).

TU has the longest carbon side chain, consisting of 11 carbon atoms compared to seven and eight for TC and TE respectively, which accounts for its longer duration of action (39,40). One disadvantage of these formulations is the necessity for IM injection. For TU, levels should be measured prior to each subsequent injection (3). In a randomized, parallel treatment group study of 406 subjects with low serum testosterone, two doses of Vogelxo® were compared to a testosterone patch and placebo gel (36).

Hemoglobin and hematocrit levels (to detect polycythemia) should be checked periodically in patients receiving long-term androgen administration. The half-life of testosterone cypionate when injected intramuscularly is approximately eight days. Testosterone cypionate injection, USP, for intramuscular injection, contains testosterone cypionate which is the oil-soluble 17 (beta)-cyclopentylpropionate ester of the androgenic hormone testosterone. Studies have found both an increase and decrease in high-density lipoprotein cholesterol. An increase was found to occur after 3 months increasing further during 12 months (43), after 6 months, (35) or close to 1 year (44). Below is a list of medications that can interact with testosterone cypionate.